South San Francisco Vacations from $331

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Your South San Francisco Vacation

Lock in a South San Francisco vacation package and get ready to experience the best of this lively city. Consider basing yourself in the neighborhood of Sharp Park, which is great for families, nature and golfing. Make your trip to South San Francisco even more fun by including some sightseeing. San Francisco State University, Cow Palace and Pacifica State Beach are among the major attractions worth exploring. Browse Expedia's wide range of travel options and start organizing your ideal vacation to South San Francisco now.

The Latest South San Francisco vacation packages

Price found within the past 48 hours. Click for updated prices.
SF Central Hotel

SF Central Hotel

2 out of 5
South of Market
Save 100% on your flight
Price was $590, price is now $331 per person
$331
per person
Mar 24 - Mar 28
found 1 day ago
Roundtrip flight included
Carlsbad (CLD) to San Francisco (SFO)
6.2/10 (862 reviews)
No parking needed. The facility looked decent on the outside, but very dated and run down on the inside. It's a place to sleep for the night. The Becks motel/hotel in the Castro was a much better experience. Some older hotels just have that lived in look.

Reviewed on Oct 26, 2025

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was $1,674, price is now $934 per person
$934
per person
Mar 24 - Mar 28
found 1 day ago
Roundtrip non-stop flight included
Carlsbad (CLD) to San Francisco (SFO)
9/10 Wonderful! (7,092 reviews)
Very nice hotel, clean rooms, great location

Reviewed on Jan 12, 2026

Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
Ingold - Milldale
Save 100% on your flight
Price was $916, price is now $516 per person
$516
per person
Mar 24 - Mar 28
found 1 day ago
Roundtrip flight included
Carlsbad (CLD) to San Francisco (SFO)
9/10 Wonderful! (4,699 reviews)
Room was clean. Staff was nice. Amenities were good. Breakfast was wonderful.

Reviewed on Jan 12, 2026

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $2,150, price is now $1,312 per person
$1,312
per person
Feb 11 - Feb 16
found 1 day ago
Roundtrip flight included
Dallas (DAL) to San Francisco (SFO)
9.2/10 Wonderful! (470 reviews)
Amazing service and ammenties are nice

Reviewed on Jan 12, 2026

Nob Hill Hotel

Nob Hill Hotel

4 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $670, price is now $426 per person
$426
per person
Mar 16 - Mar 21
found 12 hours ago
Roundtrip flight included
Denver (DEN) to San Francisco (SFO)
7.8/10 Good! (1,004 reviews)
It is close to everything!

Reviewed on Jan 8, 2026

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Discover the most popular places to visit in South San Francisco

Golden Gate Bridge illuminated at night with city lights in the background in California, USA

Golden Gate Bridge

Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Golden Gate Bridge
Pier 39 which includes a city, signage and street scenes

Pier 39

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Pier 39
Golden Gate Park featuring a garden and flowers

Golden Gate Park

This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

Golden Gate Park

What to do in South San Francisco

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz San Francisco Bay Cruise with Night Option

Alcatraz Visit with Night Option and SF Bay Cruise

$139
per adult
96% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
San Francisco City Lights Cruise

San Francisco City Lights Cruise (2-hours)

$58
per adult
94% of travellers recommend
San Francisco City Lights Cruise (2-hours)
See all activities in South San Francisco

South San Francisco Hotel Deals

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

2 out of 5
326 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $68 total per night from Jan 23 to Jan 24
$68 total
Jan 23 - Jan 24
Total with taxes and fees
5.8/10 (3,040 reviews)
It’s okay for an overnight stay.

Reviewed on Jan 11, 2026

Travelodge by Wyndham San Francisco Airport North
DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd

4 out of 5
275 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $134 total per night from Jan 25 to Jan 26
$134 total
Jan 25 - Jan 26
Total with taxes and fees
8.4/10 Very Good! (2,062 reviews)
The room was excellent and the staff were super friendly and accommodating. The breakfast was my favorite part. Made to order breakfast each morning and it was soo delicious. Thank you double tree, will definitely stay there again!!

Reviewed on Jan 8, 2026

DoubleTree by Hilton San Francisco South Airport Blvd
Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point

3.5 out of 5
250 Gateway Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $172 total per night from Jan 23 to Jan 24
$172 total
Jan 23 - Jan 24
Total with taxes and fees
8.4/10 Very Good! (1,252 reviews)
Food was great and rooms were adequate.

Reviewed on Jan 7, 2026

Embassy Suites by Hilton San Francisco Airport Oyster Point
See all 5,169 properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best South San Francisco Vacation Packages

South San Francisco Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Francisco Intl. Airport (SFO)
Population
67,300
Max Temp Winter
60ºF
Max Temp Summer
70ºF
Top Sights
Ocean Beach, California Academy of Sciences and San Francisco Zoo

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Frequently asked questions

How much does a South San Francisco vacation package cost?
You can grab a vacation package to this destination from $331 on Expedia. However, how much your vacation to South San Francisco costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to South San Francisco?
You're likely to find reduced prices and better availability in February, October and December. Check out our cheap South San Francisco vacation packages and you could land some great off-season discounts.
How many days is enough for South San Francisco?
With a well-organized itinerary, you can easily tick off the top South San Francisco attractions in a few days. But if you'd like to explore off the beaten track or go on day tours, think about booking your South San Francisco vacation for longer.
Is it worth booking a vacation package to South San Francisco?
It's no wonder a South San Francisco vacation is on the must-do list of many travelers. Well-known attractions like K1 Speed San Francisco are just the beginning of what you can explore here.
How to find the best South San Francisco package deals?
Finding a cheap South San Francisco package deal is a breeze with Expedia. Once you've entered your preferred dates and destination under our "Packages" tab, set your budget range, apply a few filters and browse what's available. You can tailor your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most pocket-friendly South San Francisco package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a South San Francisco vacation as a package?
You can enjoy significant savings on your next South San Francisco retreat by booking a tailored vacation package. Check the "Package" heading, then select your destination and travel dates to browse the best hotel and flight prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to South San Francisco?
Enjoy fantastic discounts by reserving your flights early with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu South San Francisco adventure.
How to plan a trip to South San Francisco?

  1. Choose your dates: What you'd like to do in South San Francisco and your favorite season can help you decide when to travel.
  2. Set a budget: Factor in expenses like flights, transportation and food when calculating how much to set aside for your trip to South San Francisco. Then, choose a hotel that fits your budget, whether that's an economical stay or a deluxe getaway.
  3. Organize your South San Francisco getaway with our trip planning tool: Look for and book stays and experiences all in one place. You can also collaborate with your group to plan an unforgettable trip to South San Francisco together.
  4. Determine how many days away: Start by compiling a list of the sights and activities you want to get to in South San Francisco. Then, estimate how long you'll need at each, including any travel time.
  5. Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to pick a South San Francisco vacation package that brings all your bookings together.
  6. Book any excursions or activities: Now to the fun part — locking in everything you want to see and do. Explore some of the best things to do in South San Francisco in South San Francisco and book your tickets in advance to save time (and maybe some money too!).

Does Expedia offer Book Now, Pay Later South San Francisco vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your South San Francisco trip across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up great vacation packages with payment plans as soon as you see them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.